Under natural conditions the embryo is continously exposed to dynamic stimuli generated by the peristaltic movement of the tuba uterina and the ciliated epithelium. Especially the first five days after ovulation friction and movement are an integral part of the micro environment of the embryo. In order to provide physiological conditions in the in-vitro culture there have been attempts to integrate these physical phenomena in the IVF laboratory. It is believed that through these movements the removal of pollutants and the optimal supply of fresh nutriants is ensured, subsequently having a positive effect on embryo development. Former studies have shown that the use of paddles or vibration resulted in better embryo quality and in increased pregnancy rate. The complexity and high cost of these methods, however, as well as the fact that these methods are not applicable in commerical benchtop-incubators prevent the routine use in the common IVF laboratory. In the present study, the oocytes of 20 patients were divided into two groups and cultivated in two different benchtop-incubators. A small speaker was placed next to each culture dish, which, in the control group was set on 'mute' whereas in the study group was turned to full volume. Throughout the whole duration of cultivation, at an interval of twen-ty minutes, a single tone with a frequency of 432 Hz was played for one minute. The evaluation of the results showed no significant difference regarding embryo development between study group and control group. The use of soundwaves in in-vitro culture of human embryos is a new attempt to provide physiological conditions for the embryo and is a method that can be easily integrated in rou-tine laboratories. It was clearly established that the application of acoustic waves does not have a negative effect on the embryo. To make further conclusions follow-up studies, for example using different frequencies, and a more homogenous patient collective will be necessary.