Genesis models of mental disorders often exhibit gaps, and condition models are not considered in the totality of variables (Steinhausen, 2004). However, the determination of individual risk and protective factors, as well as certain factor constellations, shows a decisive element for the promotion and maintenance of mental health (Becker, 1997; Noeker & Petermann, 2008). The aim of this study is the empirical verification of a comprehensive migration-specific model of mental health of children and adolescents. For this purpose, a number of theoretically described child-, family- and migration-related risk and protective factors are surveyed and their influence on parameters of mental health (anxiety, depression, self-esteem, intelligence, sense of coherence, behavioral problems) is analysed. The present study includes a total of 302 Austrian and Turkish children and adolescents with a migration background. The sample consists of clinical and non-clinical participants aged 7-18.The identified model shows that socio-economic status (family income) affects family factors (acculturative stress, parent-child conflicts, family members with mental-health problems, traumatic experiences of the mother). These in turn influence child-related factors (development-related variables) which determine the mental health level of the child. By means of this model, migration-related protective factors (good knowledge of the native language, low acculturative stress, few experiences of discrimination, regular social contacts with Austrians) are identified, that are essential to implement further preventive interventions in this area.