Affective pictures provoke increased visual cortex activation. Enhanced activation of sensory modalities, when dealing with emotional salient cues compared with neutral cues, is not limited to the visual domain. Thus, this so called affective modulation concerns the auditory domain, too. Accordingly, auditory emotional sounds also modulate the neuronal activity. Affective modulation does not only occur in sensory areas but also in parietal areas. This region of the brain is involved in attention-related processes. The aim of the present NIRS-study was to figure out whether emotional salient sounds were able to modulate the human brain activity within the auditory cortex, as well as the neuronal activity within parietal areas. Previous studies demonstrated that auditory cortex is modulated by positive and negative valent stimuli. This study focused on specific emotions (disgust, fear). All twenty-nine male participants had normal hearing abilities and were not affected by any neurological disorders. Therefore the participants were instructed to listen to affective (disgust, fear) and neutral stimuli, which all consisted of human vocal sounds. The affective ratings, which were assessed after the NIRS-measurement, pointed out that the target emotions were evoked successfully. The analysis of the neuronal activation, on the contrary, did not lead to definitive results. Only neutral sound stimulation led to enhanced activation within the right auditory cortex. Therefore, there seems to be a discrepancy between the self-reported emotions and physiological data. Furthermore, the results of the explorative correlations give occasion to further emotion research by paying attention to the research of personality traits.