Bibliographic Metadata

Title
A pulsatile model for the cardiovascular system including a model for the baroreceptor dynamics / vorgelegt von Asghar Ali
Additional Titles
Modelling the Baroreceptor Loop
AuthorAli, Asghar
CensorKappel Franz ; Goswami Nandu
Published2012
Description74 Bl. : 2 Zsfassungen ; Ill., graph. Darst.
Institutional NoteGraz, Univ., Diss., 2012
Annotation
Abweichender Titel laut Übersetzung der Verfasserin/des Verfassers
Zsfassung in dt. und engl. Sprache
LanguageEnglish
Bibl. ReferenceOeBB
Document typeDissertation (PhD)
URNurn:nbn:at:at-ubg:1-40140 Persistent Identifier (URN)
Restriction-Information
 The work is publicly available
Files
A pulsatile model for the cardiovascular system including a model for the baroreceptor dynamics [2.97 mb]
Links
Reference
Classification
Abstract (German)

In der vorliegenden Dissertation wird, basierend auf in der Literatur vorhandenen Modellen für das Herzkreislaufsystem und dessen Komponenten ein Kompartment-model für das kardiovaskuläre System entwickelt, welches insbesondere ein Submodell für den pulsatil arbeitenden linken Ventrikel und ein Submodell für die Barorezeptordynamik enthält. Die in der Arbeit präsentierten Ergebnisse von Simulationsrechnungen zeigen, dass Resonanzeffekte zu einer deutlichen Herzfrequenzvariabilität führen können

Abstract (English)

The baroreceptor reflex functions to restore the blood pressure back to its normal level whenever the blood pressure deviates from this level. Therefore the baroreceptor mechanism plays a central role in short-term control of the cardiovascular system. This mechanism provides rapid negative feed back control of arterial blood pressure. The dynamics of baroreflex variation and its control are not yet full understood. The aim of this thesis is to develop a dynamic global pulsatile model of the cardiovascular system including a model of the baroreceptor control. We develop a global pulsatile model of the cardiovascular system including baroreflex action. For this purpose we use a non pulsatile model adopted from the earlier work of Kappel and Peer [14] and a simplified pulsatile left heart model by Olufsen et al. [18]. The pulsatile global model for the cardiovascular system incorporates all necessary subsystems such as systemic and pulmonary circulations, right and left ventricles etc. This model includes also Starling's law of the heart, the Bowditch effect and the baroreceptor model of Polly et al. [23]. In this study we are not validating this model against specific data sets fact we are providing qualitative comparison to well documented physiological system performance.

Stats
The PDF-Document has been downloaded 67 times.