In modern times industrial agglomerations and network organizations are essential for both, economic development and generating competitive advantages across one region such as startup enterprises. Furthermore, a strong cooperation of economy, science and research as well as the warranty of an impeccable knowledge and technology transfer are decisive to confer a competitive advantage within one region. The reason for that is on the one hand the tremendous acceleration of production and innovations cycles and on the other hand the considerable increase of competitors. As a consequence, a specific advancement of clusters, networks and startups is worthwhile. With this in mind the main goal of this thesis is to show the interdependencies between Styrian clusters together with network organizations and startups in Graz, as those depict not only enhancements of the business location but do also increase economic expansion. The concept of clusters is covered in the theory of this thesis, where the focus is on Porter`s Diamond Model to expose the competitive advantages of clusters. Subsequently, the thesis elaborates on the Styrian network region as well as on the entrepreneurial ecosystem with regard to the location of Graz and the pre-existing support measures for startups in Graz. To investigate how the Styrian industry clusters and the Creative Industries Styria are influencing the success of startups settled in Graz and how they are profiting from startup ideas, nine expert interviews are conducted. For the evaluation of the expert interviews a qualitative content analysis is used. As a completion, a future consideration in view of optimization of the disposable supportive measures for startups in Graz is displayed.