The amount of dystopian literature and other media products concerned with an apocalypse has dramatically increased in recent years. Readers have shown great interest in literary works which deal with the end of the world and particularly with what happens after cataclysmic events. Margaret Atwood, one of Canadas most prominent contemporary writers, has published several dystopian novels; among them The Handmaids Tale (1985) and her most recent novel The Heart Goes Last (2015). Her MaddAddam trilogy deals with a post-apocalyptic society struggling to survive after a man-made plague epidemic has nearly extinguished humanity. Cormac McCarthy, in his Pulitzer Prize-winning novel The Road, deals with an abandoned dystopian wasteland, and a father and son who have survived an unknown calamitous event. Both authors use literature to raise awareness of environmental issues, as well as the dangers of science and religious extremism, and the potential downfall of humanity. The aim of this thesis is to compare and contrast Oryx and Crake, The Year of the Flood, MaddAddam and The Road with regard to certain thematic aspects, namely, religion, feminism, and ecocriticism. This analysis will attempt to achieve a better understanding of the post-apocalyptic worlds created by McCarthy and Atwood, and, to some extent, offer new ways of thinking about humanitys current behaviour.