In the following study, the impact of social exclusion and disgust were explored. Disgust is understood as a protective reaction and defense mechanism against pathogenic substances and thus creates a distance, while in the social exclusion through exclusion from system, a distance is created. 89 participants took part in an online survey, which collected personality traits such as disgust propensity or disgust sensitivity from the subjects. Afterwards, the participants were invited to university and randomly assigned to one of three intervention conditions (social exclusion, social inclusion or control group). Following the intervention, which was implemented with the help of a fictional computer game called MatchingMinds, there was an image presentation with disgust, fear and neutral scenes. The subjects rated their disgust, anxiety, valence and arousal when viewing the scenes. An enhanced disgust reaction by the social exclusion group was anticipated. Results showed that when looking at anxiety or disgust scenes neither disgust nor fear of the excluded or included subjects compared to the control group were perceived differently. However, in comparison to the control group the exclusion group showed a decreased arousal when confronted with disgust and fear scenes. Perhaps the social exclusion was recovered during the instruction of image presentation. Their also could be a dampening of negative reactions to negative stimuli by the regulation of the social exclusion by positive stimuli. The arousal could also be lower in the exclusion group, because social excluded people shield against negative stimuli on the basis of a selective bias. In future research, the paradigm should be optimized. For example the questionnaire primary needs questionnaire should be used to check the manipulation of social exclusion.