Infections during pregnancy are risks, for both mother and child, which should not be under-estimated. The acronym STORCH is used for a group of pathogens that cause congenital and perinatal infections. The acronym STORCH stands for: Syphilis, Toxoplasmosis, Others (Bacterial Vaginosis, Chlamydia, Gonorrhea, Listeriosis, Group B Streptococcus, viral Hepatitis, HIV, Measles and Mumps, Parvovirus B19, Varicella/Zoster, Candidiasis a mycosis), Rubella, Cytomegalovirus, Herpes simplex virus. Up to the 20th week of pregnancy, viral infections are the greatest danger to the unborn child. Bacterial infections are especially dangerous during birth process. Due to pregnancy, the treatment must be adjusted in order not to endanger the unborn child. In this work the infections are described individually, especially the effects in an unborn caused by an infection during pregnancy, the diagnosis and recommended therapy.